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KMID : 0363219690070010043
Korean Journal of Dermatology
1969 Volume.7 No. 1 p.43 ~ p.47
A Case of Nodulo-bullous Urticaria Pigmentosa
ܦÔÔÑÎ/Byun, Dong Kil
ÑÑá¦üº/ì÷ùÓçµ/ÑÑܹòÅ/Kim, Se Whan/Lim, Han Yung/Kim, Byung Chik
Abstract
A case of urticaria pigmentosa, the first case of riddulo-bullods *ariety in Korea, is herein, described.
A 4-month old female baby was brought to our hospital by her mother wish the presenting signs of darkish brown infiltrated macules and nodules scattered on the trunk, neck, and extremities.
The first lesion was noticed by her mother as a pea simed flat macule of pinkish brown, which was seated on the right shin at birth. For the period of 4 months, it his developed into multiple similar macules on the above mentioned areas, and most of them became gradually to the nodules with lichenoid surface. She also experienced frequent bullae on them and occasional facial flushing without any specific cause.
A strong stroke, performed on the nodule, produced a severe whealing reaction followed by marked erythema around it and facial flushing ensued.
The histologic findings of the nodule revealed massive infiltration of cuboidal cells throughout the entire dermis which proved to be mast cells on toluidine blue staining.
Oral administration of the reserpine and periactin proved to be effective in this case.
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